Post-COVID-19 patients had a higher rate of pathologic aortic PWV with >10 m/s (p = 0.001) and higher values of aortic PWV, augmentation index, IMT of the common carotid, axillary and superficial femoral artery, ADMA, SDMA, kynurenine/tryptophan ratio, vWF antigen and activity, homocysteine and CD31+/CD42b– EMP compared to healthy controls (p < 0.001; p = 0.009; p < 0.001; p < 0.001; p < 0.001; p = 0.001; p = 0.043; p = 0.001; p = 0.002; p = 0.004; p = 0.004; p = 0.020, respectively). This evidence concerns the gene PECAM1 and COVID-19.