The associations of two SNPs (rs1401982, a common intronic variant, and rs17249754, a common intergenic variant with the strongest association of the SNPs) in the ATP2B1 region with both BP and risk of hypertension susceptibility were previously found by GWASs (6, 7, 11) and replicated in the Japanese (8, 9), Korean (10), East Asian (12), and Chinese populations (13). This evidence concerns the gene ATP2B1 and hypertensive disorder.