CYP17A1 and Hypertension: Furthermore, according to genetic dominance model analysis, three SNPs (rs1004467, rs11191548, and rs17249754) and two haplotypes (CYP17A1 rs1004467G-rs11191548C and ATP2B1 rs1401982G-rs17249754A) were negatively correlated with hypertension risk, while the rs1401982 SNP and the other two haplotypes (CYP17A1 rs1004467A-rs11191548T and ATP2B1 rs1401982A-rs17249754G) were positively associated with hypertension risk (p ≤ 0.002).