This analysis is based on the medical history of the patient and his family, potentially untreated hypertension, actual lipid levels, hepatic (prolonged prothrombin time) and renal impairment, and an analysis of relevant coagulation laboratory tests and exclusion of anemia and thrombocytopenia, which together with low fibrinogen and von Willebrand factor (usually high in COVID-19) levels refer to a bleeding risk. The gene discussed is VWF; the disease is hypertensive disorder.