Animals fed with HF diet and treated with L. johnsonii N6.2, alone or in combination with BB, showed lower levels of SREBP1 (HF control vs. HF_LJ: p < 0.05, HF control vs. HF_BB/LJ: p < 0.01) as well as SCAP (HF control vs. HF_LJ: p < 0.05, HF control vs. HF_BB/LJ: p < 0.01) (Figure 7). The gene discussed is SREBF1; the disease is hydrops fetalis.