1.2—In the presence of ARDs, the presence of some autoantibodies (anti-JO1, anti-PL 7, anti-PL12, anti-SSA Ro, anti-MDA 5, anti-Scl70, anti-PM/Scl, anti-Th/To) increase the risk of developing ILD. The gene discussed is CALR; the disease is interstitial lung disease.