LMNA and laminopathy: To date, over 15 different diseases have been described, associated with 498 mutations in the LMNA gene as reported by UMD-LMNA, universal mutations database.1 Laminopathies are characterized by a wide range of clinical phenotypes, in which one type of tissue is most often affected, mainly of mesenchymal origin, for example, lipodystrophy (damage to adipose tissue), mandibuloacral dysplasia (damage to bone tissue), cardiomyopathy and muscular dystrophy (damage of the heart and skeletal muscles) (Rankin and Ellard, 2006).