UPF1 and cancer: Lin et al. (2019) suggested that DANCR can facilitate angiogenesis by regulating the DANCR/miR-145/VEGF axis in a manner of ceRNA. Additionally, DANCR showed a cancer-promoting property by negatively regulating UPF1. Enhanced UPF1 in OC cells was able to partly reverse the promotion of cell proliferation and migration by DANCR (Pei et al., 2019).