EZH2 and breast cancer: Li et al. (2017c) revealed that DANCR expression was downregulated in BC cells as well as tumor tissues. It was verified that DANCR mediated EZH2 degradation and attenuated EMT and metastasis in BC. Another study from the same lab also showed that DANCR could inhibit TGF-β-induced EMT progress and BC metastasis by downregulating RUNX2 expression (Li et al., 2017b; Figure 5).