TPM1 and colorectal carcinoma: Bi et al. (2020) revealed that LINC01116 was highly expressed in CRC tissues compared to normal tissues, and patients with high expression of LINC01116 had a very poor prognosis. LINC01116 knockdown substantially prevented the migration, proliferation, and invasion of CRC cells and activated cell apoptosis. Emerging evidence showed that a large number of patients were commonly diagnosed at terminal stages with high expression of LINC01116. Liang et al. (2021) identified that LINC01116 facilitated the growth of CRC cells and tumorigenicity through the downregulation of TPM1 expression.