ALB and HIV infectious disease: Considering the important influence that plasma protein binding exerts on systemic drug disposition, this study sought to (1) quantitatively describe the time-course of serum/plasma protein concentrations (i.e., albumin and AAG) in pregnant and postpartum women living with HIV, (2) compare concentrations to values reported in pregnant and postpartum women without HIV infection, and (3) generate computational functions that describe the trajectory of serum/plasma protein concentrations in pregnant and postpartum women living with HIV to inform the prospective development of PBPK models.