Comprehensive analysis of the research results and general conclusions of previous scholars at home and abroad leads to questions of whether the mTOR signaling pathway in lymphocytes of patients with systemic lupus erythematosus is not mainly involved in regulating the level of autophagy in lymphocytes, whether there is a regulatory defect in the mTOR signaling pathway in lymphocytes of patients with systemic lupus erythematosus, and whether there are more important signaling pathways involved in the regulation of lymphocyte autophagy in patients with systemic lupus erythematosus? The gene discussed is MTOR; the disease is systemic lupus erythematosus.