MAP2K4 and infection: C. elegans glp-4; sek-1 worms have mostly been used in these studies (aside from the wild-type strain, N2) because of their inability to produce progeny at 25°C due to the glp-4 mutation and their susceptibility to pathogens due to sek-1 mutation, thus making the worms immunocompromised for infection by opportunistic human fungi (Huang et al., 2014; Okoli and Bignell, 2015; Ahamefule et al., 2020a)