Mice colonized with the CRS microbiota exhibited disrupted colonic mucosal barrier before and after DSS exposure, while A. muciniphila supplementation significantly enhanced the expression of MUC2 (Figure 8A) and increased the number of goblet cells and MUC2-positive cells in each villus (Figures 8B, –E). Here, MUC2 is linked to congenital rubella syndrome.