In fact, HOTAIR has the potential to be an effective therapeutic target for many types of cancer, where abnormal HOXD expression has been found to be associated with cancer progressions, such as cancers in breast, stomach, colon, cervix, lung, and liver (11, 12, 24, 36, 52–54, 158, 159, 169, 170). The gene discussed is HOTAIR; the disease is cancer.