In subsequent studies, thrombocytosis was found to be caused by IL-6 in Granulocyte-Colony-Stimulating Factor (G-CSF)-producing tumors and by both granulocyte-CSF and IL-6 in Granulocyte Macrophage-Colony-Stimulating Factor (GM-CSF)-producing tumors (57). Here, IL6 is linked to thrombocytosis disease.