Proliferation and/or motility of cancer cells were promoted after LPA signalling through the LPAR1 in colon, gastric, and breast cancer (64–67), LPAR2 in colon and renal cancer (68–70), LPAR3 in colon, pancreatic, and breast cancer (71–73), LPAR4 in fibrosarcoma (74), and LPAR6 in hepatic and pancreatic cancer (75, 76). The gene discussed is LPAR2; the disease is familial pancreatic carcinoma.