found that in breast cancer 4T1-bearing mice, RYP combined with Platycodon grandiflorum (RP) effectively decreased the content of inflammatory marker Fibrinogen and inflammation-associated cytokines IL-6 and IL-1β in the lung tissue, improved the pulmonary inflammatory microenvironment resulted from breast cancer, and prevented the lung metastasis of breast cancer (64). Here, IL1B is linked to breast carcinoma.