In addition, Ciji-Hua’ai-Baosheng improved the immune function of H-22 tumor-bearing mice after treatment with chemotherapy and alleviated CTX-induced colitis, manifested as elevated lymphocytes in spleen, augmented IL-2, IFN-γ and TNF-α, and the reduced IL-6 in serum and tumor tissues (69). This evidence concerns the gene IL6 and neoplasm.