Furthermore, we analyzed The Cancer Genome Atlas (TCGA) database and found that only RUNX3 expression was positively associated with poor prognosis in AML (RUNX3, p = 0.02; TMEM50B, p = 0.14; TGOLN2, p = 0.81; Figure 1B). The gene discussed is RUNX3; the disease is acute myeloid leukemia.