Furthermore, we analyzed The Cancer Genome Atlas (TCGA) database and found that only RUNX3 expression was positively associated with poor prognosis in AML (RUNX3, p = 0.02; TMEM50B, p = 0.14; TGOLN2, p = 0.81; Figure 1B). This evidence concerns the gene TMEM50B and acute myeloid leukemia.