Of populations with reported allele frequencies and an appreciable sampling size (≥100 individuals), only Hong Kong Chinese and Japanese have DPA1*02:02 allele frequencies (55.8% and 43.5%, respectively; Gonzalez-Galarza et al., 2020; Allele Frequency Net Database, 2020) above its observed frequency (29.0%) in the COVID-19 positive cohort analyzed herein. This evidence concerns the gene HLA-DPA1 and COVID-19.