SLC22A6 and hyperuricemia: Eucommiae cortex alcohol extract [79] and anthocyanin [80] can enhance the expression of ATP-binding cassette subfamily G member 2 (ABCG2), OAT1, and organic anion transporter (OAT3) protein in hyperuricemia (HUA) and GA animal models and accelerate uric acid excretion by regulating the mechanism of renal reabsorption for uric acid.