TGFB1 and renal fibrosis: The results showed that compared with the control group, the renal fibrosis indexes TGF-β1, LN, and HA were significantly increased in the alcohol group and the difference was statistically significant (P < 0.05); after 6 weeks of treatment, the alcohol + dapagliflozin group and the alcohol + losartan group had lower TGF-β1, LN, and HA (P < 0.05) than the alcohol group.