Compared to the lupus group, the ADSC group showed lower p62 expression and higher Beclin 1 and LC3-II/LC3-I expression (P < 0.05), and the miR-20a group had a much stronger effect on inducing autophagy compared with the ADSC group (P < 0.05, Figure 3(a)). This evidence concerns the gene SQSTM1 and systemic lupus erythematosus.