AKT1 and hepatocellular carcinoma: As shown in Figure 9, in addition to increased UFM1 expression when B3GALT5-AS1 ov in HCC cells, both of the phosphorylated AKT (p-AKT) and the phosphorylated PI3K (p-PI3K) decreased compared with the NC group and further affected the apoptosis pathway-related proteins Bcl-2 downregulation and Bax upregulation.