Moreover, there were some regulators, such as TCF4, FOSL2, BCL6, RXRA, CUX1, CREBBP, E2F3, BCL11A, EGR1, FOXG1, TP53, JMJD1C and STAT4, which were both changed in expression and were predicted to be the regulators of DEGs in HD (Supplementary Dataset S9). The gene discussed is JMJD1C; the disease is Huntington disease.