Moreover, the available monkey dataset showed genes such as CAMKV, KCNIP2, OPRD1, RGS9, HRH3, ADORA2A, KLF16, CNR1, OPRK1, FOXP1, NR4A1, TESC, GSN and RARB that were dysregulated in monkey model of HD (Supplementary Figure S6B). The gene discussed is OPRK1; the disease is Huntington disease.