JUN and Huntington disease: The second analysis uncovered many differentially expressed transcription factors and epigenetic regulators, some of which were indicated as potential master regulators in HD by previous studies, e.g., JUN related transcription factors (Perrin et al., 2009), FOS related transcription factors (Cabanas et al., 2017), CBP (Giralt et al., 2012), EGR1 (Chandrasekaran and Bonchev, 2016) and ELK1 (Yildirim et al., 2019).