MBD2 and cancer: Several studies support the hypothesis that aberrant expression of m6A regulators, i.e., “writers” (methyltransferases), “readers” (binding proteins), and “erasers” (demethylases), potentially participates in carcinogenesis, cancer development, or tumor-suppressive activities in various types of cancer, including ccRCC (Wang Q. et al., 2020; Huang et al., 2020).