The expression of genes related to macrophage infiltration (F4/80) and the ratio of mRNA expression of genes involved in macrophage M1 polarization state (CD11c/CD206 and CD11c/CD209e) were significantly elevated in arthritic mice compared to control lean, suggesting that arthritis induces the infiltration and presence of M1 macrophages in adipose tissue (Figures 2C–E). Here, MRC1 is linked to Arthritis.