CXCR2 and hepatocellular carcinoma: Another report also proved that overexpression of CXCR2 on CAR T cells increase homing capability of CXCR2-expressing CAR T cells toward hepatocellular carcinoma cells-producing CXCL1, CXCL2, CXCL3, CXCL5, CXCL6, and CXCL8 (38).