AS chemokine CCL20 is also overexpressed in various types of cancer like colon adenocarcinoma (COAD), rectum adenocarcinoma (READ) and stomach adenocarcinoma (STAD), therefore, overexpression of CCR6 in CAR T cells might be an effective strategy to overcome insufficient infiltration of CAR T cells into CCL20-expressing tumor sites. The gene discussed is CCR6; the disease is colon adenocarcinoma.