In line with this notion, Adachi et al., reported that overexpression of IL-7 and CCL19, as two essential cytokines for generation of less-differentiated, long-lived non-exhausted (CAR) T cells and recruitment of endogenous DCs and T cells, in CAR T cells (termed 7x19 CAR T cells) increased infiltration of DCs and T cells into tumor sites following 7 × 19 CAR T cell therapy. The gene discussed is CCL19; the disease is neoplasm.