BAL samples from children with CF show significantly higher levels of both subsets of CD66b+ granulocytes [CD16-CD66b+ (median 4.02% vs 0.03%, p=0.0003) and CD16+CD66b- (median 8.4% vs 0.35%, p=0.03)] (Figure 1B). The gene discussed is CEACAM8; the disease is cystic fibrosis.