IFNG and chronic myelogenous leukemia, BCR-ABL1 positive: In KHYG-1 cells treated with the mixture of six LAB from kefir, mRNA expression and IFN-gamma (interferon gamma) secretion levels were increased which enhanced the cytotoxicity to human chronic myelogenous leukemia K562 cells and colorectal tumor HCT116 cells (Yamane et al., 2018).