As a first step in the investigation of a possible direct effect of FSH on the aorta, the mRNA expression or localization of the FSHR in aortic tissue should be assessed, to reveal if there are differences in FSHR gene expression or density on cells in the aorta and/or number of cells positive for FSHR, between AAA and non-diseased aortic tissue. Here, BRD2 is linked to triple-A syndrome.