Among the HFpEF-DEPs and HTN-DEPs, there were 7 co-DEPs, including haptoglobin (Hp), coenzyme Q9 (COQ9), serotransferrin (Tf), major prion protein (Prnp), acetyl-CoA acetyltransferase, mitochondrial (Acat1), translocase of inner mitochondrial membrane 44 (Timm44), and ATP-binding cassette sub-family B member 6 (Abcb6; Figure 2C). This evidence concerns the gene PRNP and hypertensive disorder.