NPPA and myocardial infarction: At week 14, we observed significant increases in gene expression of pro-hypertrophic markers ANP (Figure 6A), BNP (Figure 6B) and β-MHC (Figure 6C), and gene expression of pro-fibrotic markers TGF-β (Figure 6D), Collagen-I (Figure 6E), collagen-III (Figure 6F) and TIMP-2 (Figure 6G) in the non-infarct zone in VEH-treated MI + STNx rats compared with VEH-treated SHAM + SHAM rats.