Galectin-1 and 3 play important roles in the pathogenesis of neuroinflammatory and neurodegenerative disorders such as multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), Alzheimer's disease (AD), Parkinson's disease, Huntington's disease, and prion disease (Barake et al., 2020). This evidence concerns the gene LGALS1 and Parkinson disease.