In accordance with these observations, patients with iatrogenic ATTRv amyloidosis, meaning recipients of domino-transplanted, fully functioning organs carrying an amyloidogenic TTR mutation, have so far not been observed to develop symptoms other than neuropathy and cardiomyopathy [29–32], which both result from the presence of unstable TTR in the peripheral circulation. The gene discussed is TTR; the disease is cardiomyopathy.