ACE and digestive system disorder: Between-subset comparison of concomitant medications revealed that higher proportion of Subset 1 subjects were treated with anti-aggregants (36.4% in Subset 1 vs 14.0% in Subset 2, p = 0.002), polyferment drugs (11.4% in Subset 1 vs 0.8% in Subset 2, p = 0.004) and medications for gastrointestinal disorders (6.8% in Subset 1 vs 0% in Subset 2, p = 0.016), whereas the proportion of subjects treated with angiotensin converting enzyme inhibitor was higher in Subset 2 (45.7% in Subset 2 vs 27.3% in Subset 1, p = 0.002).