KRAS and neoplasm: Accordingly, cell type–specific lung tumor models have been generated by utilizing either club cell‐specific CCSP‐Cre‐ or type II epithelial cell–specific SPC (surfactant protein C)‐Cre–mediated expression of oncogenes (e.g. Kras) or deletion of tumor suppressors (e.g. Trp53 and Pten) [51].