MAPK6 and lung carcinoma: For example, while ERK3 depletion had little effect on the growth of lung cancer cell lines H1299 and H1650 that express wild‐type KRAS [3, 6], it greatly reduced cell growth and/or anchorage‐independent colony formation of KRASG12C‐positive H23 and H2122 NSCLC cell lines and xenograft tumor growth of the Calu‐1 cell line also expressing KRASG12C [6].