Erythropoietin resistance index (ERI) as defined by weight-adjusted weekly erythropoietin dose (Units) per dry weight (kg) per hemoglobin (g/dl) was significantly higher in patients with heart failure (Mean ERI 25.4 vs. 19.3 Units/kg per g/dl, p < 0.05) (Table 2). Here, EPO is linked to heart failure.