Numerous studies over the last decade have shown that the cGAS‒STING signaling pathway plays an important regulatory role in pathogen infection, malignancies, and autoimmune disorders by regulating both innate immunity and adaptive immunity (Cheng et al., 2020; Kwon and Bakhoum, 2020; Wan et al., 2020). This evidence concerns the gene STING1 and Autoimmunity.