HTT and amyotrophic lateral sclerosis: The ALS associated C9-dipeptide repeat and FUS proteins are known to localize substantially to RNA stress granules in cultured cells and/or to inclusions that contain stress granule markers like TDP-43 or Ataxin-2 in vivo (Liu-Yesucevitz et al. 2010; Bentmann et al. 2012; Bakthavachalu et al. 2018; Chew et al. 2019) To test whether Htt-polyQ granules also similarly sequester stress-granule markers, we examined Htt-polyQ aggregates in vivo and in eye imaginal discs for colocalization with stress granule markers.