ANXA11 and immunoglobulin G4-related sclerosing disease: Of note, the expression of annexin A11 in other organs commonly affected by IgG4-related disease (such as pancreas, salivary glands, prostate) shows a similar expression pattern to that observed in the liver: a compelling predominance of annexin A11 expression in the epithelial HCO3−-secreting cells targeted by the disease.10 This observation, together with the present study, provides a rationale to further investigate the role of annexin A11 and the HCO3− umbrella in the pathogenesis of systemic IgG4-related disease.