Correspondingly, α-Syn seeders showed lower mean CSF levels of LAMP2 (PD: 1.00) and VGF (PD: 0.93; DLB: 0.57) compared to non-seeders (PD: LAMP2 1.27, p = 0.05, VGF 1.36, p = 0.014; DLB: VGF 0.90, p = 0.05) (Additional file 6: Table S5). Here, VGF is linked to Lewy body dementia.