To couple our MCF10A series findings with patient data, we identified super-enhancers in 47 estrogen receptor positive (ER +) patient samples [36], 10 triple-negative breast cancer (TNBC) patient samples, and 11 triple-negative breast cancer cell lines (TNBCC) [37] (Additional file 9: Table S6). Here, ESR1 is linked to triple-negative breast carcinoma.