To investigate the functional relevance of this finding, we next mimicked acute inflammatory response by stimulating T cells with PHA and measured T-cell activation with flow cytometry using CD69 staining in an independent cohort of 23 PD (mean age 68.9 ± 10.5; f/m = 6/17) patients and 14 healthy controls (mean age 67.3 ± 12.2; f/m = 6/8) (Fig. 4A). The gene discussed is CD69; the disease is Parkinson disease.