SNHG4 and diabetic retinopathy: It is downregulated in patients with neonatal pneumonia (NP) [30], diabetic retinopathy (DR) [19], acute cerebral infarction (ACI) [20], and acute myeloid leukaemia (AML) [21] and is upregulated in gastric cancer (GC) [31], renal cell carcinoma (RCC) [32], glioblastoma (GBM) [33], neuroblastoma [34], colorectal cancer (CRC) [35], etc. The aberrant expression of SNHG4 has been proven to be closely related to the genesis, occurrence and progression of various diseases.