It is downregulated in patients with neonatal pneumonia (NP) [30], diabetic retinopathy (DR) [19], acute cerebral infarction (ACI) [20], and acute myeloid leukaemia (AML) [21] and is upregulated in gastric cancer (GC) [31], renal cell carcinoma (RCC) [32], glioblastoma (GBM) [33], neuroblastoma [34], colorectal cancer (CRC) [35], etc. The aberrant expression of SNHG4 has been proven to be closely related to the genesis, occurrence and progression of various diseases. This evidence concerns the gene SNHG4 and renal cell carcinoma.