Immunohistochemistry assessment revealed that the tumor cells tested positive for melan-A (Fig. 2c), human melanoma black-45 (HMB-45), caldesmon, and S100 and negative for cluster of differentiation (CD)56, chromogranin A, synaptophysin, AE1/AE3, desmin, α-smooth muscle actin, CD34, CD117, and CAM5.2. The gene discussed is CALD1; the disease is neoplasm.