CCNE1 and colorectal carcinoma: In turn, DICER1 is targeted by DELTA133P53, targets miR-9, miR-15a-5p, miR-196a-5p, and is associated with AGO2 and UPF1. Regulatory molecules including DELTA133P53, cyclin E (CCNE1) and STAT3, which play roles in CRC development, are also actors in the network [17–22].