The isoform miR-31-P targets and represses DICER by translational repression, whereas miR-31-M targets and represses CSBPα, STK40 and E2F2, in HCT116 colon cancer cells, suggesting that specific genes regulated by miR-31 might be isoform dependent [36]. This evidence concerns the gene STK40 and malignant colon neoplasm.