Nine genes were annotated to within 500 Kb of the association signal and the sentinel SNP (rs17773014) is a significant eQTL for AKR1B1 in whole blood with the AML risk allele associated with higher transcript levels (PBH = 5.32 × 10−23) (Supplementary Table 8). Here, AKR1B1 is linked to acute myeloid leukemia.