We also identified a borderline statistically significant association with cytogenetically normal AML for rs17773014 (OR 1.26, 95% CI 1.15–1.37; P = 4.09 × 10−7), which maps close to the AKR1B1 gene on chromosome 7q33 (Fig. 3d). Here, AKR1B1 is linked to acute myeloid leukemia.