Analysis of data from GWAS 4 validated (P < 0.05) two of the associations identified in the discovery GWAS meta-analysis, with consistent direction and magnitude of effect sizes across all four studies, including 11q13.2 (rs4930561, KMT5B; P = 2.15 × 10−8) for all AML irrespective of sub-type (N = 4018) and 6p21.32 (rs3916765, HLA-DQA2; P = 1.51 × 10−10) for cytogenetically normal AML (N = 1287). The gene discussed is HLA-DQA2; the disease is acute myeloid leukemia.