HLA-DQB1 and acute myeloid leukemia: We identified strong statistical evidence for an association with cytogenetically normal AML for rs3916765 (OR 1.72, 95% CI 1.46–2.03; P = 1.51 × 10−10), which maps to the HLA locus on 6p21.32, intergenic to HLA-DQB1 and HLA-DQA2 within the major histocompatibility (MHC) class II region (Fig. 3b).