As might be predicted from the screening viability studies, myeloma light chains from donor B induced ~ 700-fold increase in the quantity of NGAL released by cells in rotating or static spinpods (Fig. 9c), rotating 30,708 ± 2435 vs. media 42 ± 4 ng/mL and static 36,261 ± 2339 vs. media 53 ± 4 ng/mL) whereas myeloma light chains from donor C induced only ~ 100-fold increase in NGAL release (rotating 4722 ± 89 ng/mL and static 5107 ± 113 ng/mL). This evidence concerns the gene LCN2 and plasma cell myeloma.