Rotation induced significantly greater quantities of GM-CSF in the media control (45.8 ± 3.7 ng/mL for rotating vs. 30.6 ± 1.7 ng/mL static; p = 0.004, W = 39, n1 = 7, n2 = 6) and after stimulation with myeloma light chains from donor C (Fig. 9a, 188 ± 8 ng/mL rotating vs. 139 ± 11 static; p = 0.005, W = 33, n1 = 7, n2 = 5,) but not myeloma light chains from donor B (41 ± 2 ng/mL rotating vs. 36 ± 2 ng/mL static). Here, CSF2 is linked to plasma cell myeloma.