NLRP3 and focal segmental glomerulosclerosis: Although NLRP3 expression in E-cadherin-positive tubular epithelial cells from focal segmental glomerulosclerosis (FSGS) and LN was somewhat higher compared to DN, IgAN, we could find NLRP3 mainly expressed in E-cadherin-negative tubular epithelial cells (Fig. 5).