Generally, we observed different “categories” of Fin56-induced ferroptosis in our BC cells (Figure S6): (1) autophagy-dependent GPX4 degradation (253J, T24), (2) potentially autophagy-independent GPX4 degradation (J82; Figs. 1 and 7A), and (3) independent of GPX4 degradation (RT-112; Figs. 1 and 7A). This evidence concerns the gene GPX4 and breast cancer.