A total of 317 patients with nr-axSpA and elevated CRP and/or active sacroiliitis on MRI (MRI positive or MRI negative) were enrolled in C-axSpAnd and were randomised to either CZP 200 mg Q2W (n = 159) plus NBBM or placebo (n = 158) plus NBBM. Here, CRP is linked to Sacroiliac arthritis.