Diagnosis can often be a challenge in non-radiographic axial spondyloarthritis (nr-axSpA); the presence of sacroiliitis on magnetic resonance imaging (MRI), human leukocyte antigen (HLA)-B27 and acute phase reactants such as serum C-reactive protein (CRP) remain the most reliable diagnostic tests but with limited specificity and/or sensitivity [1–3]. Here, CRP is linked to Sacroiliac arthritis.